Introduction

The Department of Oral Pathology and Microbiology was established in the year 1999 at Sree Mookambika Institute of Dental Sciences. This specialty of Dentistry includes Dental Anatomy, Histology, Embryology and Pathology. Forensic Odontology, an emerging field in Dentistry also comes under this department.

Dental Anatomy and Histology forms the foundation to better understanding of Clinical Dentistry for first year undergraduates and Oral Pathology teaches third year undergraduates to identify various pathologic conditions clinically as well as on histo-pathologic examination. The department has a well-equipped histopathology lab for tissue processing where routine H & E staining, special staining, Immunohistochemistry and Exfoliative Cytology are carried out regularly to facilitate precise and accurate diagnosis for appropriate treatment plan.  There is a Haematologic laboratory where blood investigations can be done.

  • To provide knowledge of basic dental anatomy and morphology which is absolutely essential for further study of Dentistry
  • To identify various pathologic conditions clinically as well as histopathologically for appropriate treatment plan
  • To acquire knowledge in the basics of molecular based techniques, immunology, genetics and to accomplish research in oral cancer and other oral diseases.

To become a centre of excellence in the field of Oral Pathology through futuristic development by introducing new technologies like

  • Cell culture labs
  • Stem cell research
  • Karyotyping
  • Molecular studies

Facilities

  • A well-equipped clinical examination room, student's laboratory, and a museum with numerous mounted specimens, models and posters

  • A well-equipped histopathology lab - routine H & E staining, special staining, Immunohistochemistry and Exfoliative Cytology are carried out regularly.

  • A hematologic laboratory where blood investigations can be done

  • A unit with sophisticated instruments including
      o Trinocular research microscope with camera
      o Polarizing microscope
      o Darkfield microscope
      o Phase contrast microscope
      o Pentadigital microscope with camera

Research Activities

The Head of the Department is guiding PhD students of other Universities.

Completed Research
Name of the PG Guide / Co-Guide Title of the Thesis Year of Completion

Dr. Arun Mohan
..........................................................................

Guide - Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL
............................................................................

Immunohistochemical expression of podoplanin in normal mucosa, oral epithelial dysplasia and oral squamous cell carcinoma.
2014
Dr. George Jacob

Guide - Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL 

Immunohistochemical expression of survivin in normal mucosa, oral epithelial dysplasia and oral squamous cell carcinoma.
2014
Dr. Gomakumar

Guide – Dr.Girish K.L,
Co-Guide – Dr.Isaac Joseph T

Comparing the reliability of barr bodies, palatal rugae and mesio distal dimensions of maxillary canine and central incisors in determination of sex
2014
Dr. Krishna Prasad

Guide - Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL

Expression of Cyclin D1 in normal mucosa, oral epithelial dysplasia and oral squamous cell carcinoma.

2015

Dr. Sudha Rani

Guide - Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL

Expression of PTEN in normal mucosa, oral epithelial dysplasia and oral squamous cell carcinoma
2015
Dr. Akhil

Guide - Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL

Determination of accuracy of radiological age estimation using Indian version of Demirjian’s formula in population of Kanyakumari district
2016
Dr. Aldrin Jerry

Guide -Dr.Girish K.L,
Co-Guide – Dr.Isaac Joseph T

Qunatitative and qualitative evaluation of argyrophilic nucleolar organiser region in normal mucosa, inflammatory,potentially malignant and malignant oral lesions.

2016

Dr. Jeslin Mary

Guide - Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL

Evaluating the genotoxic effects of silver amalgam and resin basd restoration. Micronuclei based comparative study on oral exfoliated cells.

2016
Dr. Vidya S

Guide - Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL

A comparative analysis of mandibular ramus and mental foramen in sex determination among the Kanyakumari population

2017

Dr. Ashitha

Guide -Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL

Comparing the efficiency of coconut oil and palm oil with xylene as clearing agent in conventional Haematoxylin and Eosin Histopathological staining procedures

2017

Dr. Ani Simila

Guide -Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL

A comparative analysis of CDSF and Proliferating Cell Nuclear Antigen(PCNA) in oral squamous cell carcinoma-An immunohistochemical study.

2018

Quantitative analysis of apoptotic cells in normal oral mucosa, oral epithelial dysplasia, OSCC by using Methyl green Pyronin stain.
2017
Dr. Swetha

Guide - Dr. Isaac Joseph. T,
Co-Guide - Dr.Girish KL

Quantitative estimation of Langerhans cells in normal oral mucosa,inflammatory mucositis, oral epithelial dysplasia and oral squamous cell carcinoma using CD1a Antibody- An Immunohistochemical study.

2018

Assesment of methylmercury level in (blood ) and genotoxic effects in oral exfoliated cells in chronic fish eaters iun Kanyakumari dist
2017
Dr. Abilasha

Guide -Dr. Isaac Joseph. T,
Co-Guide - Dr.Prasanth T

Candida species isolation in Type 2 Diabetic patients using Chrom agar media

2018

Dr. Rajalakshmi

Guide - Dr. Isaac Joseph. T,
Co-Guide - Dr.Prasanth T

Tongue prints in Forensic Dentistry

2018

Completed Research
Name of the PG Scholar Name of the Guide / Co-Guide Title of the Research Project

Dr. Abilasha
..........................................................................

Dr. Isaac Joseph T.
Dr. Girish K. L.
..........................................................

Detection of Candida species in saliva of Diabetic and Non-Diabetic individuals using Chrom Agar media and PCR- A comparative study

Dr. Isaac Joseph T.
Dr. Prasanth T. ,
Dr. Geetha Vargheese

Analysis of Genotoxic Effects of Mobile phone radiation in Buccal mucosa using Giemsa Stain and Comet Assay : A Comparative Evaluation

Dr. Rajalakshmi

Dr. Isaac Joseph T.
Dr. Prasanth T.

Quantitative estimation of salivary Interleukin-8 in Oral Lichen Planus patients with and without Type 2 Diabetes Mellitus
Identification of Cell Cannibalism in Oral Squamous Cell Carcinoma and it’s correlation with worst pattern of invasion and lymphocytic response
Dr. JeyaPriya

Dr. Isaac Joseph T.,
Co-Guide - Dr.Girish KL

Evaluation of Salivary pH, flowrate, buffering capacity of pre and post menopausal women and correlation of various lesions and conditions in oral cavity

Dr. Isaac Joseph T.
Dr. Prasanth T. ,
Dr. Angelin D.

Highlighting the stromal mucin using special stains : A key to identify the pattern & intensity in Tumour progression

Dr. Veenah

Dr. Isaac Joseph T.,
Dr. Girish K. L.

Evaluation of salivary levels of tumour necrosis factor alpha and interleukin 10 in patients with recurrent apthous stomatitis

Dr. Isaac Joseph T.
Dr. Prasanth T. ,
Dr. Geetha  Vargheese

Evaluation of mitotic index, apoptotic index and turnover index in different grades of oral epithelial dysplasia and oral squamous cell carcinoma

Dr. Percy Ida

Dr. Prasanth T.,
Dr. Isaac Joseph T,
Dr. Girish K. L.

Evaluation and comparison of cancer stem cell markers Aldehyde Dehydrogenase 1 and Sex Determining Region- Y Box 2 in Oral Squamous Cell Carcinoma and Oral Verrucous Carcinoma – An Immunohistochemical study

Staff Publications
Title of the Paper Author Name of the Journal Year of Publication
Genotoxic effects of saliva amalgam &composite restoration cohort case control study in oral exfoliated cells

Dr. T. Isaac Joseph
......................................................

Contemporary clinical dentistry
2018
Virtopsy an integration of forensic science and imageology
Dr. T. Isaac Joseph
Journal of forensic dental science
2017
Minor salivary gland changes in oral epithelial dysplasia and oral squamous cell carcinoma
Dr. T. Isaac Joseph
Journal of Clinical and Diagnostic Research
2016
Linear IgA dermatosis adult variant with oral manifestation
Dr. T. Isaac Joseph
Journal of Oral and Maxillofacial Pathology
2015

Teaching Programme

For Undergraduates
  • Individual training in identification and carving of primary & permanent teeth
  • Develop skills in age estimation using plaster casts.
  • Identify dental anomalies through natural tooth specimens and plaster casts.
  • Clinical and microscopic identification of pathological conditions of the oral cavity.

Regular class tests and internal assessment examinations are conducted to monitor and improve the overall performance of undergraduate students.

For Post graduates
  • The post graduate programme was started in the year 2012 and consists of three post graduates per year. They are given intense training to be skilled and efficient Oral and Maxillofacial Pathologists at the level of histopathologic and molecular techniques and include

    • Participation in preliminary research activities.
    • Acquire knowledge about the subject through presentation of seminars, journal discussions and case reporting.
    • Mastering the skills of histopathology techniques, special staining, immunohistochemistry and basic molecular and genetic techniques.
    • Interaction in national and international level activities through participation in conferences, PG conventions, CDE programmes, preconference courses and presentation of poster and paper.
    • Training in undergraduate teaching programme.

Conference and CDEs

CDEs conducted by the Department
  • Plasmoblastic lymphoma mimicking multiple myeloma in a seronegative HIV patient. Academic forum, SMIDS. (22-2-16)
  • Linear IgA Dermatosis, Case presentation, SMIMS, Kulasekaram. (15-10-16)
Conferences and CDEs Attended
  • XI Annual conference of Kairali Society of Oral and Maxillofacial Pathology – Kollam, 2014
  • XXIII National Conference of Indian Association of oral & maxillofacial pathology – Bangalore, 2014
  • XIII National Triple O Symposium – Bangalore, 2015
  • XIII IAFO National Conference Forensic Odontology – Mysore, 2015
  • Research Methodology Workshop-PMS Dental College – Trivandrum, 2014
  • Research Data Management- Azeezia Dental College – Kollam, 2014
  • Workshop on Age determination in Forensic Odontology-Rajas Dental College, Kavalkinaru, 2014
  • Updates on prevention and control of Oral Cancer – RCC, Trivandrum, 2016
  • 18th IAOP – XXV IAOMP 2016 Conference – Chennai, 2016
  • CDE Work shop – Forensic odontology, “Age estimation revisited” – PMS Dental College, 2017

Faculty as Speaker/Guest Lecturer

Dr. Isaac Joseph T.

Conference Year Topic Presented
13th NATIONAL CONFERENCE IAFO-JSSDC, Mysore
2015
Use of Insects and Microbes in crime investigation- A New Dimension in Forensic Sciences
9th NATIONAL CONFERENCE IAFO-VMSDC, Salem
2011
Forensic entomology
31st TAMIL NADU STATE DENTAL CONFERENCE (VILCON 2013), Pondicherry
2013
Forensic odontology- Dentist perspective
5th TOMA CONFERENCE, Chennai
2009
Salivary Gland Disorders

Dr. Prasanth T.

Conference Year Topic Presented
18th IAOP –INTERNATIONAL CONFERENCE, Chennai
2016
Comparison of Serum and Saliva cotinine levels among smokers and non-smokers by using ELISA
INTERNATIONAL SYMPOSIUM ON HEAD AND NECK TUMORS, Manipal
2015
Small cell neuroendocrine tumor of oral cavity-a rare entity.
6TH ANNUAL MEETING OF ASIAN SOCIETY OF ORAL AND MAXILLOFACIAL PATHOLOGY, Hyderabad
2014
Clinico-pathologic correlations
7TH WORLD WORKSHOP ON ORAL HEALTH AND DISEASES IN AIDS, Hyderabad
2014
Sterilization of Instruments in AIDS Patients
XXIII NATIONAL CONFERENCE OF INDIAN ASSOCIATION OF ORAL & MAXILLOFACIAL PATHOLOGY, BANGALORE
2014
Multiple Myeloma vs Plasmoblastic Lymphoma

Awards/ Recognitions

Awards / Merits Year Faculty Name Event
ICMR Grants
2018
Dr. Isaac Joseph T.
Comparative analysis of CD 57 and PCNA expression in oral squamous cell carcinoma – An IHC study.